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NYVEPRIA (pegfilgrastim-apgf) Patient Counseling Information


Advise the patient to read the FDA-approved patient labeling (Patient Information and Instructions for Use).

Advise patients of the following risks and potential risks with NYVEPRIA:

  • Splenic rupture and splenomegaly
  • Acute Respiratory Distress Syndrome
  • Serious allergic reactions
  • Sickle cell crisis
  • Glomerulonephritis
  • Capillary Leak Syndrome
  • Aortitis

Instruct patients who self-administer NYVEPRIA using the single-dose prefilled syringe of the:

  • Importance of following the Instructions for Use.
  • Dangers of reusing syringes.
  • Importance of following local requirements for proper disposal of used syringes.

This product's label may have been updated. For full prescribing information, please visit

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